Kidney transplantation and COVID-19 pandemic: synthesis of literature on procedures performed in Brazil
Keywords:
Transplantation, Kidney, COVID-19, BrazilAbstract
Transplantation is the most efficient alternative to treat terminal functional kidney failure. To synthesize the literature on the topic, this systematic review sought to retrieve evidence that empirically analyzed the frequency of kidney transplantation in Brazil, relating it to the COVID-19 pandemic. The PUBMED, LILACS and SCIELO databases were consulted using the descriptors: “Transplantation”, “Kidney”, “COVID-19”, and “Brazil”. Thus, 146 studies were retrieved and only six were included in the review. The review showed that the COVID-19 pandemic had a negative impact on the number of kidney transplants, increased the transplant waiting list, reduced the number of donors, and there were reports of infections and deaths among patients undergoing kidney treatment and transplant recipients during the pandemic. These findings emphasize the need for more research and attention in the area of kidney transplantation and mitigate the effect of health crises similar to COVID-19.
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ARAÚJO, A. Y. C. C. DE. et al.. Declínio nas doações e transplantes de órgãos no Ceará durante a pandemia da COVID-19: estudo descritivo, abril a junho de 2020. Epidemiologia e Serviços de Saúde, v. 30, n. 1, p. e2020754, 2021.
ASSOCIAÇÃO BRASILEIRA DE TRANSPLANTES DE ÓRGÃOS (ABTO). Registro Brasileiro de Transplantes: dados numéricos da doação de órgãos e transplantes realizados por estado e instituição no período: janeiro / setembro – 2020. São Paulo: ABTO,2020. Disponível em: <https://site.abto.org.br/wp-content/uploads/2020/08/RBT2020-3tri-1.pdf>. Acesso em 25 set. 2023a.
ASSOCIAÇÃO BRASILEIRA DE TRANSPLANTES DE ÓRGÃOS (ABTO). Registro Brasileiro de Transplantes: dimensionamento dos transplantes no Brasil e em cada estado (2013-2020). São Paulo: ABTO,2020. Disponível em: <https://site.abto.org.br/wp-content/uploads/2020/08/2020_populacao_1.pdf>. Acesso em 25 set. 2023b.
AUBERT, O. et al. COVID-19 pandemic and worldwide organ transplantation: a population-based study. The Lancet Public Health, v. 6, n. 10, p. e709–e719, out. 2021. https://doi.org/10.1016/s2468-2667 (21)00200-0
AUGUSTINE, J. Kidney transplant: New opportunities and challenges. Cleveland Clinic Journal of Medicine, v. 85, n. 2, p. 138–144, fev. 2018. https://doi.org/10.3949/ccjm.85gr.18001
BORDES, S. J. et al. Trends in US Kidney Transplantation during the COVID-19 Pandemic. Cureus, v. 12, n. 12, p. e12075, 14 dez. 2020.
BOYARSKY, B. J. et al. Early national and center-level changes to kidney transplantation in the United States during the COVID-19 epidemic. American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, v. 20, n. 11, p. 3131–3139, Nov. 2020.
BRASIL. Ministério da Saúde. Doação de Órgãos. Disponível em: https://www.gov.br/saude/pt-br/composicao/saes/snt/doacao-de-orgaos/doacao-de-orgaos. Acesso em: 10 jul. 2023a.
BRASIL. Ministério da Saúde. Secretaria de Atenção Especializada à Saúde. Sistema Nacional de Transplantes. Disponível em: https://www.gov.br/saude/pt-br/composicao/saes/snt. Acesso em: 15 de setembro de 2023b.
DE ANDRADE, L. G. M. et al. Impact of the COVID-19 Pandemic on Solid Organ Transplant and Rejection Episodes in Brazil’s Unified Healthcare System. Journal of Clinical Medicine, v. 11, n. 21, p. 6581, 6 nov. 2022.
GARCIA, V. D.; PÊGO-FERNANDES, P. M. Organ transplantation and COVID-19. Sao Paulo Medical Journal, v. 139, n. 4, p. 301–304, Jul. 2021.
HADI, Y. B. et al. Outcomes of COVID-19 in Solid Organ Transplant Recipients: A Propensity-matched Analysis of a Large Research Network. Transplantation, v. 105, n. 6, p. 1365, jun. 2021.
KHAIRALLAH, P. et al. The impact of COVID-19 on kidney transplantation and the kidney transplant recipient - One year into the pandemic. Transplant International: Official Journal of the European Society for Organ Transplantation, v. 34, n. 4, p. 612–621, abr. 2021.
LIBERATI, A. et al. The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration. Annals of Internal Medicine, v. 151, n. 4, p. W-65, 18 ago. 2009.
LOUPY, A. et al. Organ procurement and transplantation during the COVID-19 pandemic. Lancet (London, England), v. 395, n. 10237, p. e95, 23 maio 2020.
MANARA, A. R. et al. Donation and transplantation activity in the UK during the COVID-19 lockdown. Lancet (London, England), v. 396, n. 10249, p. 465–466, 2020.
MINISTÉRIO DA SAÚDE. Nota Técnica: Gerenciamento do Risco Sanitário da Epidemia de COVID-19 para a Doação e Transplantes de Órgãos, Tecidos e Células-Tronco Hematopoéticas. Brasília: Ministério da Saúde, 2022. Disponível em: https://www.gov.br/saude/pt-br/assuntos/covid-19/notas-tecnicas/2022/nota-tecnica-gerenciamento-do-risco-sanitario-da-epidemia-de-covid-19-para-a-doacao-e-transplantes-de-orgaos-tecidos-e-celulas-tronco-hematopoeticas.pdf. Acesso em: 6 jun. 2024.
PASSONI, R. et al. The impact of COVID-19 on kidney transplant activities in Brazil: a descriptive study. Sao Paulo Medical Journal, v. 141, n. 1, p. 60–66, Jan. 2023.
PESSOA, J. L. E.; DONNINI, O. A.; MONTEIRO, F. Impact of the COVID-19 Pandemic on Organ Donation and Transplantation in São Paulo, Brazil. Transplantation Proceedings, abr. 2022.
PESTANA, J. M. To transplant or not to transplant during a pandemic? Brazilian Journal of Nephrology, v. 45, n. 2, p. 142–143, jun. 2023.
POPAY, J. et al. Guidance on the Conduct of Narrative Synthesis in Systematic Reviews. 2006.
RIBEIRO JUNIOR, M. A. F. et al. Impact of COVID-19 on the number of transplants performed in Brazil during the pandemic. Current situation. Revista do Colégio Brasileiro de Cirurgiões, v. 48, p. e20213042, 2021.
SALVALAGGIO, P. R. et al. An International survey on living kidney donation and transplant practices during the COVID‐19 pandemic. Transplant Infectious Disease, v. 23, n. 2, p. e13526, abr. 2021.
SHARMA, V. et al. The impact of the COVID-19 pandemic on renal transplantation in the UK. Clinical Medicine, v. 20, n. 4, p. e82–e86, jul. 2020.
SOLER, M. J. et al. Impact of the COVID-19 pandemic on Spanish Nephrology Services. Nefrologia, v. 40, n. 6, p. 579–584, 2020.
TEICHMANN, P. DO V. et al. One-year impact of COVID-19 pandemic on renal replacement therapy and kidney transplantation in a tertiary center in Southern Brazil. Brazilian Journal of Nephrology, v. 45, n. 2, p. 210–217, jun. 2023.
TEPEL, M. et al. Pretransplant characteristics of kidney transplant recipients that predict posttransplant outcome. Frontiers in Immunology, v. 13, 2022.
VIANA, L. A. et al. Transplanting Kidneys from Donors with SARS-CoV-2 RNA Positivity in Brazil: Early Success under a Detailed Surveillance Approach. Transplantation, v. 106, n. 12, p. e517–e519, 1 dez. 2022.
WOLFE, R. A. et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. The New England Journal of Medicine, v. 341, n. 23, p. 1725–1730, 2 dez. 1999.
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