Apresentações Atípicas de Artrite Reumatoide: Uma Revisão Integrativa da Literatura
DOI:
https://doi.org/10.14295/idonline.v17i66.3782Palavras-chave:
artrite reumatoide, manifestações atípicas, doença autoimuneResumo
A artrite reumatoide é uma doença inflamatória autoimune de caráter sistêmico que afeta predominantemente as pequenas articulações, apresentando frequentes manifestações extra articulares e, por vezes, atípicas. Este trabalho tem por objetivo realizar uma revisão integrativa da literatura quanto apresentações atípicas da artrite reumatoide. Seguimos o método de revisão narrativa da literatura a partir de uma busca no banco de dados eletrônicos BVS para a identificação de artigos dos últimos 2 anos seguindo os itens de Diretrizes para Revisões Sistemáticas e Metanálises (PRISMA). Na estratégia de busca utilizamos os seguintes descritores em saúde: “artrite reumatoide” and “sintomas incomuns” OR “clínica atípica”. Esta patologia possui uma ampla ocorrência de sintomas que se acumulam ao longo da vida do paciente e possuem características inespecíficas. As manifestações atípicas da artrite reumatoide elevam a piora do prognóstico e reduzem a sobrevida do indivíduo, logo são de suma importância clínica.
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ALETAHA, Daniel; SMOLEN, Josef S. Diagnosis and Management of Rheumatoid Arthritis. Jama, [S.L.], v. 320, n. 13, p. 1360, 2 out. 2018. DOI: https://doi.org/10.1001/jama.2018.13103
AN, Hyo Jin; TIZAOUI, Kalthoum; TERRAZZINO, Salvatore; CARGNIN, Sarah; LEE, Keum Hwa; NAM, Seoung Wan; KIM, Jae Seok; YANG, Jae Won; LEE, Jun Young; SMITH, Lee. Sarcopenia in Autoimmune and Rheumatic Diseases: a comprehensive review. International Journal Of Molecular Sciences, [S.L.], v. 21, n. 16, p. 5678, 7 ago. 2020. DOI: https://doi.org/10.3390/ijms21165678
BEHRENS, Frank; BURMESTER, Gerd-Rüdiger; FEUCHTENBERGER, Martin; KELLNER, Herbert; KUEHNE, Cornelia; LIEBHABER, Anke; WASSENBERG, Siegfried; GERLACH, Johannes; ZORTEL, Max; HOFMANN, Michael W.. Characterisation of depressive symptoms in rheumatoid arthritis patients treated with tocilizumab during routine daily care. Pathogenesis Of Rheumatoid Arthritis: one year in review 2022, [S.L.], v. 40, n. 3, p. 551-559, 22 mar. 2022. DOI: https://doi.org/10.55563/clinexprheumatol/yu55rd
BERDUGO-HURTADO, Fernando; MARTÍN-LAGOS-MALDONADO, Alicia; MARTÍNEZ-DOMÍNGUEZ, Ana Patricia; VIDAL-VÍLCHEZ, Begoña; BENAVENTE-FERNÁNDEZ, Alberto. Linitis gástrica: un reto diagnóstico. Gastroenterología y Hepatología, [S.L.], v. 45, n. 5, p. 375-376, maio 2022. DOI: https://doi.org/10.1016/j.gastrohep.2020.08.019
BERMAN, Brian; COCKERELL, Clay J.. Pathobiology of actinic keratosis: ultraviolet-dependent keratinocyte proliferation. Journal Of The American Academy Of Dermatology, [S.L.], v. 68, n. 1, p. 10-19, jan. 2013. DOI: https://doi.org/10.1016/j.jaad.2012.09.053
CHANG, C. M., LIN, J. R., & FU, T. C. Associations Between Sarcopenia, Heart Failure and Myocardial Infarction in Patients With Systemic Lupus Erythematosus and Rheumatoid Arthritis. Frontiers in medicine vol. 9 882911. 28 Jun. 2022, doi:10.3389/fmed.2022.882911, Acesso em: 06 dez. 2022 DOI: https://doi.org/10.3389/fmed.2022.882911
CHEN X, ZHANG M, WANG T, LI Y, WEI M. Influence factors of extra-articular manifestations in rheumatoid arthritis. Open Medicine, vol. 15, no. 1, 2020, pp. 787-795. https://doi.org/10.1515/med-2020-0217 Acesso em: 07 dez. 2022 DOI: https://doi.org/10.1515/med-2020-0217
CHENG, Q., CHEN, X., WU, H., DU, Y. Three hematologic/immune system-specific expressed genes are considered as the potential biomarkers for the diagnosis of early rheumatoid arthritis through bioinformatics analysis. J Transl Med. 2021;19(1):18. Published 2021 Jan 6. https://doi.org/10.1186/s12967-020-02689-y DOI: https://doi.org/10.1186/s12967-020-02689-y
CONWAY, Richard; LOW, Candice; COUGHLAN, Robert J.; O'DONNELL, Martin J.; CAREY, John J.. Methotrexate and Lung Disease in Rheumatoid Arthritis: a meta-analysis of randomized controlled trials. Arthritis & Rheumatology, [S.L.], v. 66, n. 4, p. 803-812, 28 mar. 2014. DOI: https://doi.org/10.1002/art.38322
DAS S, PADHAN P. An Overview of the Extraarticular Involvement in Rheumatoid Arthritis and its Management. J Pharmacol Pharmacother. 2017 Jul-Sep;8(3):81-86. doi: 10.4103/jpp.JPP_194_16. PMID: 29081614; PMCID: PMC5642136 , Acesso em: 06 dez. 2022
DERVENIS, Panagiotis; VASILAKIS, Panagiotis; STATHI, Theodora; GIANNOULAKOS, Georgios; DERVENIS, Nikolaos; PRAIDOU, Anna; REMPAPIS, Ioannis. Acute corneal melting one week after an uncomplicated cataract surgery in a patient who previously underwent eyelid radiation and with undiagnosed rheumatoid arthritis: a case report. Arq. Bras. Oftalmol., [S.I.], p. 1-4, 03 fev. 2021.
DUMBRA G. A. C. et al. Artrite Reumatoide de apresentação incomum: desafio diagnóstico. Medicina (Ribeirão Preto) [Internet]. 26 de novembro de 2018, Acesso em: 07 dez. 2022 http://dx.doi.org/10.11606/issn.2176-7262.v51i3p203-206 DOI: https://doi.org/10.11606/issn.2176-7262.v51i3p203-206
EKICI, Remzi; ERDEN, Abdulsamet; GÜVEN, Serdar Can; ARMAğAN, Berkan; ÖZDEMIR, Bahar; KARAKAş, Özlem; GÖK, Kevser; OMMA, Ahmet; KÜÇÜKşAHIN, Orhan; ERTEN, Şükran. Prevalence of sarcopenia and clinical implications in patients with newly diagnosed rheumatoid arthritis. Nutrition, [S.L.], v. 90, p. 111353, out. 2021. DOI: https://doi.org/10.1016/j.nut.2021.111353
FA, Zhenzong; XU, Jintao; YI, Jiu; SANG, Junjun; PAN, Weihua; XIE, Qun; YANG, Runping; FANG, Wei; LIAO, Wanqing; OLSZEWSKI, Michal A.. TNF-α-Producing Cryptococcus neoformans Exerts Protective Effects on Host Defenses in Murine Pulmonary Cryptococcosis. Frontiers In Immunology, [S.L.], v. 10, p. 1-7, 26 jul. 2019. DOI: https://doi.org/10.3389/fimmu.2019.01725
GILES JT. Extra-articular Manifestations and Comorbidity in Rheumatoid Arthritis: Potential Impact of Pre-Rheumatoid Arthritis Prevention. Clin Ther. Volume 41, Issue 7, P1246-1255, Jul, 2019, Acesso em: 07 dez. 2022 https://doi.org/10.1016/j.clinthera.2019.04.018 DOI: https://doi.org/10.1016/j.clinthera.2019.04.018
GONZÁLEZ-CHÁVEZ, Susana Aideé; PACHECO-TENA, César; CARAVEO-FRESCAS, Teresita de Jesús; QUIÑONEZ-FLORES, Celia María; REYES-CORDERO, Greta; CAMPOS-TORRES, Rosa María. Oral health and orofacial function in patients with rheumatoid arthritis. Rheumatology International, [S.L.], v. 40, n. 3, p. 445-453, 17 set. 2019. DOI: https://doi.org/10.1007/s00296-019-04440-3
HERNÁN, M.G. Bonilla; GÓMEZ-CARRERA, L.; PEÑA, M. Fernández-Velilla; WALTHER, R. Álvarez-Sala; BALSA, A.. Prevalence and clinical characteristics of symptomatic diffuse interstitial lung disease in rheumatoid arthritis in a Spanish population. Revista Clínica Española (English Edition), [S.L.], v. 222, n. 5, p. 281-287, maio 2022. DOI: https://doi.org/10.1016/j.rceng.2021.01.011
HOSODA, Chiaki; ISHIGURO, Takashi; UOZUMI, Ryuji; UEDA, Miyuki; TAKATA, Naomi; TAKAYANAGI, Noboru. Characteristics of pulmonary cryptococcosis in patients with rheumatoid arthritis. Bmj Open Respiratory Research, [S.L.], v. 8, n. 1, p. 1-8, jul. 2021. DOI: https://doi.org/10.1136/bmjresp-2020-000805
HYLDGAARD, Charlotte; HILBERG, Ole; PEDERSEN, Alma Becic; ULRICHSEN, Sinna Pilgaard; LØKKE, Anders; BENDSTRUP, Elisabeth; ELLINGSEN, Torkell. A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease: comorbidity and mortality. Annals Of The Rheumatic Diseases, [S.L.], v. 76, n. 10, p. 1700-1706, 13 jun. 2017. DOI: https://doi.org/10.1136/annrheumdis-2017-211138
IBFELT, Else Helene; JACOBSEN, Rikke Kart; KOPP, Tine Iskov; CORDTZ, René Lindholm; JAKOBSEN, Anna Svarre; SEERSHOLM, Niels; SHAKER, Saher Burhan; DREYER, Lene. Methotrexate and risk of interstitial lung disease and respiratory failure in rheumatoid arthritis: a nationwide population-based study. Rheumatology, [S.L.], v. 60, n. 1, p. 346-352, 11 ago. 2020. DOI: https://doi.org/10.1093/rheumatology/keaa327
ISHII, Keiko; KAWAKAMI, Kazuyoshi. Pattern Recognition and Host Defense Response to Cryptococcus neoformans. Medical Mycology Journal, [S.L.], v. 53, n. 4, p. 247-254, 2012. DOI: https://doi.org/10.3314/mmj.53.247
KATZ, Patricia; MARGARETTEN, Mary; TRUPIN, Laura; SCHMAJUK, Gabriela; YAZDANY, Jinoos; YELIN, Edward. Role of Sleep Disturbance, Depression, Obesity, and Physical Inactivity in Fatigue in Rheumatoid Arthritis. Arthritis Care & Research, [S.L.], v. 68, n. 1, p. 81-90, 21 dez. 2015. DOI: https://doi.org/10.1002/acr.22577
KEDRA, Joanna; SEROR, Raphaele; DIEUDÉ, Philippe; CONSTANTIN, Arnaud; TOUSSIROT, Eric; KFOURY, Elias; MASSON, Charles; CORNEC, Divi; DUBOST, Jean Jacques; MARGUERIE, Laurent. Lymphoma complicating rheumatoid arthritis: results from a french case⠳control study. Rmd Open, [S.L.], v. 7, n. 3, p. 1-9, set. 2021. DOI: https://doi.org/10.1136/rmdopen-2021-001698
KIM, H; KIM, Y; YUN, S; YU, D; LEE, Y. Association of Actinic Keratosis with Rheumatoid Arthritis and Psoriasis: a nationwide population-based study in korea. Acta Dermato Venereologica, [S.L.], p. 1-4, 2021. DOI: https://doi.org/10.2340/00015555-3877
KUMAR, Naina; SINGH, Amitkant. Trends of male factor infertility, an important cause of infertility: a review of literature. Journal Of Human Reproductive Sciences, [S.L.], v. 8, n. 4, p. 191, 2015. DOI: https://doi.org/10.4103/0974-1208.170370
LAHOZ, Ricardo M.; PAPPAS, Peter G.. Cryptococcal Infections: changing epidemiology and implications for therapy. Drugs, [S.L.], v. 73, n. 6, p. 495-504, 11 abr. 2013. DOI: https://doi.org/10.1007/s40265-013-0037-z
LEE, J; KIM, Y; HAN, K; PARK, Y; LEE, J; PARK, Y; LEE, Y. Incidence of Actinic Keratosis and Risk of Skin Cancer in Subjects with Actinic Keratosis: a population-based cohort study. Acta Dermato Venereologica, [S.L.], v. 98, n. 3, p. 382-383, 2018. DOI: https://doi.org/10.2340/00015555-2854
LOPES, F.H.A.; FREITAS, M.V.C.; DE BRUIN, V.M.S. et al. Depressive symptoms are associated with impaired sleep, fatigue, and disease activity in women with rheumatoid arthritis. Adv Rheumatol 61, 18 (2021). https://doi.org/10.1186/s42358-021-00176-6 , Acesso em: 07 dez. 2022
LOPES, Fernando Henrique Azevedo; FREITAS, Max Victor Carioca; BRUIN, Veralice Meireles Sales de; BRUIN, Pedro Felipe Carvalhedo de. Depressive symptoms are associated with impaired sleep, fatigue, and disease activity in women with rheumatoid arthritis. Advances In Rheumatology, [S.L.], v. 61, n. 1, p. 1-7, 16 mar. 2021. DOI: https://doi.org/10.1186/s42358-021-00176-6
MENA-VÁZQUEZ, Natalia; JIMENEZ-NðÑEZ, Francisco Gabriel; GODOY-NAVARRETE, Francisco Javier; MANRIQUE-ARIJA, Sara; AGUILAR-HURTADO, María Carmen; ROMERO-BARCO, Carmen María; UREÑA-GARNICA, Inmaculada; ESPILDORA, F.; PADIN-MARTÍN, María Isabel; FERNÁNDEZ-NEBRO, Antonio. Utility of pulmonary ultrasound to identify interstitial lung disease in patients with rheumatoid arthritis. Clinical Rheumatology, [S.L.], v. 40, n. 6, p. 2377-2385, 21 fev. 2021. DOI: https://doi.org/10.1007/s10067-021-05655-1
MOURA M. C. et al. Perfil dos pacientes com manifestações extra-articulares de artrite reumatoide de um serviço ambulatorial em Curitiba, Sul do Brasil. Rev. Bras. Reumatol. 2012, v. 52, n. 5, pp. 686-694. Disponível em: <>. Epub 20 Dez 2016. ISSN 1809-4570. Acesso em: 07 dez. 2022 DOI: https://doi.org/10.1590/S0482-50042012000500004
OVERMAN, Cécile L.; KOOL, Marianne B.; SILVA, José A. P. da; GEENEN, Rinie. The prevalence of severe fatigue in rheumatic diseases: an international study. Clinical Rheumatology, [S.L.], v. 35, n. 2, p. 409-415, 15 ago. 2015. DOI: https://doi.org/10.1007/s10067-015-3035-6
PAMUKCU, Melih; DURAN, Tuğba İzci̇; ULUSOY, Hasan; ALTINBAş, Kürşat. Investigation of the correlation between mood disorder symptoms and disease activity and functional status in rheumatoid arthritis patients. Turkish Journal Of Medical Sciences, [S.L.], v. 51, n. 6, p. 3008-3016, 13 dez. 2021. DOI: https://doi.org/10.3906/sag-2107-283
PEREZ-GARCIA, L. F.; RÖDER, E.; PASTOOR, H.; BOLT, H.; VAN EXEL, J.; DOLHAIN, R.. OP0303-HPR IT IS NOT JUST ABOUT THE SEX: viewpoints of dutch adult men with inflammatory arthritis regarding the impact of the disease on their sexual health. Annals Of The Rheumatic Diseases, [S.L.], v. 80, n. 1, p. 186-186, 19 maio 2021. DOI: https://doi.org/10.1136/annrheumdis-2021-eular.640
PEREZ-GARCIA, Luis Fernando; RÖDER, Esther; GOEKOOP, Robbert J; HAZES, Johanna M W; KOK, Marc R; SMEELE, Hieronymus T W; TCHETVERIKOV, Ilja; MIL, Annette H M van Der Helm-Van; KAAP, Jos H van Der; KOK, Petra. Impaired fertility in men diagnosed with inflammatory arthritis: results of a large multicentre study (ifame-fertility). Annals Of The Rheumatic Diseases, [S.L.], v. 80, n. 12, p. 1545-1552, 9 ago. 2021. DOI: https://doi.org/10.1136/annrheumdis-2021-220709
SÁNCHEZ-MEDRANO, Ana Gabriela; MARTÍNEZ-GUTIÉRREZ, Fidel; MARTÍNEZ-MARTÍNEZ, Marco Ulises; SALAS-OROZCO, Marco Felipe; VILLA-GARCÍA, Lorena Dafnee; PATIÑO-MARÍN, Nuria. Association Between Subjects with Newly Diagnosed Rheumatoid Arthritis and Dental Caries. Odovtos - International Journal Of Dental Sciences, [S.L.], p. 468-478, 19 nov. 2021. DOI: https://doi.org/10.15517/ijds.2022.49148
SANDSTRÖM T. et al. Cervical Spine Involvement among Patients with Rheumatoid Arthritis Treated Actively with Treat-to-target Strategy: 10-year Results of the NEO-RACo Study. J Rheumatol. 2020 Aug 1;47(8):1160-1164. doi: 10.3899/jrheum.190139. Epub 2019 Nov 15. PMID: 31732558 DOI: https://doi.org/10.3899/jrheum.190139
TAYLOR-GJEVRE, Regina M.; GJEVRE, John A.; SKOMRO, Robert P.; NAIR, Bindu V.; LIM, Hyun J.. Improved sleep efficiency after anti-tumor necrosis factor α therapy in rheumatoid arthritis patients. Therapeutic Advances In Musculoskeletal Disease, [S.L.], v. 3, n. 5, p. 227-233, 30 ago. 2011. DOI: https://doi.org/10.1177/1759720X11416862
UZUNASLAN, Didem; SAYGIN, Caner; HATEMI, Gulen; TASCILAR, Koray; YAZICI, Hasan. No appreciable decrease in fertility in Behçet’s syndrome. Rheumatology, [S.L.], v. 53, n. 5, p. 828-833, 24 dez. 2013. DOI: https://doi.org/10.1093/rheumatology/ket436
ZAUTRA, Alex J.; SMITH, Bruce W.. Depression and Reactivity to Stress in Older Women With Rheumatoid Arthritis and Osteoarthritis. Psychosomatic Medicine, [S.L.], v. 63, n. 4, p. 687-696, jul. 2001. DOI: https://doi.org/10.1097/00006842-200107000-00022
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Copyright (c) 2023 Melina Maria Batista Silva, Larissa Peixoto Maia, Bruna de Almeida Freixedelo, Larissa de Carvalho Bezerra, Bruna Ádria Carvalho Bringel, Caroline de Almeida Cabral Ribeiro
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